EP-2311: Biological effects of radiation dose-rate and intra-fraction breaks in stereotactic radiotherapy
نویسندگان
چکیده
منابع مشابه
Dosimetric impact of intra-fraction motion during high dose rate stereotactic vertebral radiotherapy using flattened and flattening filter free beams
Submitted Volumetric modulated arc therapy for stereotactic body radiotherapy: Planning considerations, delivery accuracy and efficiency
متن کاملIntra-fraction dose delivery timing during stereotactic radiotherapy can influence the radiobiological effect.
The sequence of incremental dose delivery during a radiotherapy fraction can potentially influence the radiobiological effect. This would be most noticeable during the long fractions characteristic of hypo-fractionated stereotactic radiotherapy and radiosurgery. We demonstrate here the spatio-temporal variation of dose delivery by the CyberKnife to a lung tumor and propose strategies to reduce ...
متن کاملSafety of high-dose-rate stereotactic body radiotherapy
BACKGROUND AND PURPOSE Flattening filter free (FFF) beams with high dose rate are increasingly used for stereotactic body radiotherapy (SBRT), because they substantially shorten beam-on time. The physical properties of these beams together with potentially unknown radiobiological effects might affect patient safety. Therefore here we analyzed the clinical outcome of our patients. MATERIAL AND...
متن کاملBiological effects of intermittent radiation in cultured tumor cells: influence of fraction number and dose per fraction.
In intensity-modulated radiation therapy (IMRT) and stereotactic irradiation using a linear accelerator, radiation is administered intermittently and one treatment session often requires 30 min or a longer time. The purpose of the present study was to investigate the effect of fractionation and dose per fraction on cell killing by irradiation in intermittent exposure. Murine EMT6 and SCCVII cel...
متن کاملBiological equivalent dose studies for dose escalation in the stereotactic synchrotron radiation therapy clinical trials.
Synchrotron radiation is an innovative tool for the treatment of brain tumors. In the stereotactic synchrotron radiation therapy (SSRT) technique a radiation dose enhancement specific to the tumor is obtained. The tumor is loaded with a high atomic number (Z) element and it is irradiated in stereotactic conditions from several entrance angles. The aim of this work was to assess dosimetric prope...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2018
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(18)32620-3